TOXICOLOGY STUDIES FOR AGROCHEMICALS
TOXICOLOGY STUDIES FOR AGROCHEMICALS
The widespread use of agrochemicals, including pesticides, insecticides, herbicides, fungicides, and fertilizers, is integral to modern agriculture. However, it also brings about unintentional exposure of the environment, animals, and humans to these substances, posing potential health risks. Rodenta Bioserve offers comprehensive toxicology studies for agrochemicals to assess their safety and mitigate associated risks.
Importance of Agrochemical Safety Testing
Human exposure to agrochemicals can occur during application, production, or consumption of foods containing pesticide residues. Therefore, it’s crucial to test agrochemicals for safety in relation to their intended use, as well as assess the toxicity of their residues to the environment, animals, and human health. Adhering to a ‘safety-first’ approach, we conduct rigorous toxicology studies using animal models, with results extrapolated to humans.
Acute Toxicity Studies
- Acute Oral Toxicity Study: Following OECD 423 and 425 test guidelines in rodents.
- Acute Inhalation Toxicity: Conducted in rats according to OECD 403 test guideline.
- Skin Sensitization Test: Utilizing OECD 406 test guideline (GPMT).
- Acute Dermal Toxicity: Assessed in rats using OECD 402 test guideline.
- Acute Dermal Irritation/Corrosion: Conducted in rabbits following OECD 404 test guideline.
- Acute Eye Irritation/Corrosion: Evaluated in rabbits according to OECD 405 test guideline.
Subacute, Subchronic, and Chronic Toxicity Studies
- 28-Day Repeat Dose Toxicity Study: In rats following OECD 407 test guideline.
- 90-Day (Sub-Chronic) Repeat Dose Toxicity Study: Conducted in rats using OECD 408 test guideline.
- Chronic Toxicity Study: Following OECD 452 test guideline.
- Carcinogenicity Study: In rats and mice according to OECD 451 & 453 test guidelines.
Genotoxicity
- Micronucleus Test (In Vivo): Conducted as per OECD 474 guidelines.
- AMES Test (Bacterial Reverse Mutation): Following OECD 471 guidelines.
- Chromosomal Aberration Test (In Vivo): Utilizing OECD 475 guidelines.
Developmental & Reproductive Toxicity (DART)
- Prenatal Developmental Toxicity: Assessed in rats and rabbits according to OECD 414 guidelines.
- Prenatal & Postnatal Developmental Toxicity: Following ICH guidelines.
- Neonatal Toxicity: Evaluated in rats and mice.
- Reproductive & Developmental Toxicity: In rats following OECD 421 & 422 guidelines.
- Male Fertility Study: Conducted in rats.
At Rodenta Bioserve, we are committed to ensuring the safety of agrochemicals through rigorous testing protocols and adherence to international guidelines.
